EBI Metagenomics

MGnifams

A metagenomics-derived protein families resource

MGnifams are derived from the MGnify protein database (release 2024_04, May 2024), which contains 717,738,164 metagenomic protein sequences. Families are built by clustering these sequences iteratively and constructing HMM profiles, capturing the diversity of proteins found across diverse environmental metagenomes.

Number of currently hosted protein families: 35459

Search by annotation Searches %term% (case-insensitive) across:
• Pfam ID & name (sequence-HMM hits)
• Pfam ID, name & description (profile-profile hits)
• FunFam ID (CATH FunFam hits)

Examples: `PF000`, `kinase`, `1.10.10`

ID	Full size	Representative length	pLDDT	pTM	Helix%	Strand%	Coil%	Inside%	Membrane-alpha%	Outside%	Signal%	Membrane-beta%	Periplasm%

MGnifams

Search by annotation Searches %term% (case-insensitive) across: • Pfam ID & name (sequence-HMM hits) • Pfam ID, name & description (profile-profile hits) • FunFam ID (CATH FunFam hits) Examples: PF000, kinase, 1.10.10

Search by annotation Searches %term% (case-insensitive) across:
• Pfam ID & name (sequence-HMM hits)
• Pfam ID, name & description (profile-profile hits)
• FunFam ID (CATH FunFam hits)

Examples: `PF000`, `kinase`, `1.10.10`